
The Challenge of Uneven Ground for Sensitive Knees
Knee discomfort is a common struggle for many, especially those living with osteoarthritis or persistent knee pain. Everyday pleasures like countryside strolls or crossing cobbled streets can soon feel intimidating when your knees ache or feel unsteady. Research shows that “knee and ankle energy absorption…significantly increased in the drop-step,” illustrating why uneven surfaces can be such a challenge for sensitive joints (Aminiaghdam et al., 2021). For anyone determined to stay active and independent, finding ways to regain stability on uneven ground is vital.
Understanding Arthrosamid—A New Approach
Arthrosamid is an innovative injectable treatment designed to ease joint discomfort, particularly in knee osteoarthritis. It works by injecting a gel-like substance into the knee joint, which enhances cushioning and reduces friction. This helps improve the joint’s natural support, making movement steadier and less painful. Recent studies have found that “PAAG provided improvement in knee OA symptoms over 24 months, in older, non-diabetic patients with lower KL grades.” It's important to remember that outcomes vary depending on individual health, and Arthrosamid is not a guaranteed cure. However, it remains a promising option for those suited to this treatment.
Free non-medical discussion
Not sure what to do next?
Information only · No medical advice or diagnosis.
The Role of Expert Care—Professor Paul Lee and MSK Doctors
When it comes to managing joint health, expert guidance is crucial. Professor Paul Lee is a leading expert in orthopaedics and rehabilitation, with extensive experience in knee conditions. He holds respected roles including Cartilage Expert and Ambassador to the Royal College of Surgeons of Edinburgh. Alongside the MSK Doctors team, he offers a supportive, professional environment where patients receive personalised assessments and advice. As research emphasises, “Further studies are warranted to validate efficacy, refine patient selection, and evaluate long-term impact,” highlighting the importance of careful decision-making with specialist input.
Restoring Stability and Reclaiming the Outdoors with Arthrosamid
Many patients hope Arthrosamid will help them feel steadier and more confident outdoors. Whether it’s enjoying countryside walks again or crossing uneven cobbles, regaining painless mobility can make a huge difference to quality of life. Movement adjustments can also help: “Leaning the trunk anteriorly…attenuates the mechanical stress on the knee,” which can ease the strain on sensitive joints when walking on uneven ground (Aminiaghdam et al., 2021). Supported by specialists like Professor Lee and the MSK Doctors team, patients can make informed choices about improving their mobility and wellbeing. It’s worth noting that “The absence of a control group and limited outcome measures should be considered,” so realistic expectations and ongoing assessment are key.
Conclusion and Disclaimer
For those whose knees protest on uneven ground, exploring new treatments like Arthrosamid alongside expert care could open up new possibilities for comfort, stability, and freedom of movement. As always, please seek personalised advice from a qualified healthcare professional.
References
- Gao, H. C. K., Akhtar, M., Creedon, C., Nar, Ö. O., & Lee, P. Y. (2025). The impact of patient factors on the minimal clinically important difference of Arthrosamid polyacrylamide hydrogel injection for knee osteoarthritis: A cohort study. Osteoarthritis and Cartilage, 33(S1), S407–S408. https://doi.org/10.1016/j.joca.2025.02.648
- Gao, H. C. K., Akhtar, M., Creedon, C., Nar, Ö. O., Verma, T., & Lee, P. Y. F. (2025). Polyacrylamide hydrogel injections in knee osteoarthritis: A PROMs-based 24 month cohort study. Journal of Clinical Orthopaedics and Trauma, 38, 103136. https://doi.org/10.1016/j.jcot.2025.103136
- Aminiaghdam, S., Karamanidis, K., & Rode, C. (2021). Uneven running: How does trunk‐leaning affect the lower‐limb joint mechanics and energetics? European Journal of Sport Science, 22(8), 1188–1195. https://doi.org/10.1080/17461391.2021.1938691
Frequently Asked Questions
- Arthrosamid is an innovative injectable gel that cushions the knee joint and reduces friction. This approach may support steadier, less painful movement for people with osteoarthritis, but individual responses vary and specialist assessment is essential.
- MSK Doctors, led by Professor Paul Lee—a renowned Cartilage Expert and Royal College of Surgeons ambassador—offers comprehensive, tailored evaluations. Their expertise ensures patients receive up-to-date options and evidence-based guidance for complex knee challenges such as osteoarthritis.
- Professor Paul Lee brings extensive experience as a cartilage specialist and surgical ambassador. His leadership, combined with rigorous, personalised assessments, enables patients to make informed decisions regarding advanced treatments and rehabilitation to improve knee joint comfort and mobility.
- While Arthrosamid can improve cushioning and support in the knee, outcomes differ between individuals. Professor Lee and MSK Doctors provide careful evaluations to help patients understand realistic expectations and identify strategies, like movement correction, to enhance outdoor mobility.
- Yes, the MSK Doctors team, under Professor Paul Lee’s guidance, recognises the importance of movement adjustments and holistic care. Their approach focuses on both advanced therapies and practical lifestyle strategies to support knee health, stability, and overall independence.
Legal & Medical Disclaimer
This article is written by an independent contributor and reflects their own views and experience, not necessarily those of Lincolnshire Hip Clinic. It is provided for general information and education only and does not constitute medical advice, diagnosis, or treatment.
Always seek personalised advice from a qualified healthcare professional before making decisions about your health. Lincolnshire Hip Clinic accepts no responsibility for errors, omissions, third-party content, or any loss, damage, or injury arising from reliance on this material.
If you believe this article contains inaccurate or infringing content, please contact us at [email protected].



